Occurrence of autoimmune pancreatitis after chronic immune thrombocytopenia in a Caucasian adolescent

Clin J Gastroenterol. 2021 Jun;14(3):918-922. doi: 10.1007/s12328-021-01383-w. Epub 2021 Mar 20.

Abstract

Autoimmune pancreatitis is a rare, distinct and increasingly recognized form of chronic inflammatory pancreatic disease secondary to an underlying autoimmune mechanism. We report on a 14-year-old boy who developed autoimmune pancreatitis, while he was under treatment with eltrombopag for chronic immune thrombocytopenia. Therapy with corticosteroids resulted in complete remission of both. This is the first report on the co-occurrence of autoimmune pancreatitis and chronic immune thrombocytopenia in childhood, and clinicians should be aware of this rare association, because early diagnosis and therapy of autoimmune pancreatitis may prevent severe complications.

Keywords: Autoimmune pancreatitis; Hematology; Immune thrombocytopenia; Immunology; Pancreas.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Autoimmune Diseases* / complications
  • Autoimmune Pancreatitis*
  • Chronic Disease
  • Humans
  • Male
  • Pancreas
  • Pancreatitis* / complications
  • Purpura, Thrombocytopenic, Idiopathic* / complications
  • Purpura, Thrombocytopenic, Idiopathic* / drug therapy