Factor V Deficiency (Owren's Disease) in a Patient at High Risk for Transfusion-Associated Circulatory Overload and Bleeding During Laser Lead Extraction

J Cardiothorac Vasc Anesth. 2022 Jan;36(1):242-245. doi: 10.1053/j.jvca.2021.02.026. Epub 2021 Feb 12.

Abstract

Congenital factor V deficiency is an extremely rare abnormality and may be associated with significant bleeding as a result of trauma or surgery. Perioperative management primarily includes the administration of fresh frozen plasma to replace the deficient clotting factor. Acute administration of multiple blood products is a risk factor for transfusion-associated circulatory overload. Herein, the case of a 71-year-old man with an ejection fraction of 13% and a history of congenital factor V deficiency who was at risk for significant bleeding and transfusion-associated circulatory overload who underwent successful complex extraction of a right atrial pacing lead is reported.

Keywords: bleeding; coagulopathy, factor V; electrophysiology.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Blood Coagulation Factors
  • Factor V Deficiency*
  • Hemorrhage
  • Humans
  • Lasers
  • Male
  • Transfusion Reaction*

Substances

  • Blood Coagulation Factors