Shock-and-kill versus block-and-lock: Targeting the fluctuating and heterogeneous HIV-1 gene expression

Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2103692118. doi: 10.1073/pnas.2103692118.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / pharmacology
  • Gene Expression / drug effects*
  • Gene Expression / genetics
  • Gene Expression Regulation, Viral / drug effects*
  • Gene Expression Regulation, Viral / genetics
  • HIV Infections / drug therapy
  • HIV-1 / genetics*
  • HIV-1 / metabolism
  • HIV-1 / pathogenicity
  • Humans
  • Virus Activation / drug effects
  • Virus Activation / physiology
  • Virus Latency / drug effects

Substances

  • Anti-HIV Agents