Breast reconstruction plays a fundamental role in the therapeutic process of breast cancer treatment and breast implants represents the leading breast reconstruction strategy. Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL), locoregional recurrence in the skin flap, and skin flap necrosis are well-known complications following mastectomy and immediate breast reconstruction (IBR). We report a case of locoregional cancer recurrence in the mastectomy flap mimicking BIA-ALCL, in a patient who underwent 6 breast procedures in four facilities across 15 years including immediate breast reconstruction with macrotextured breast implants. Despite the rate and onset of the disease, clinicians should be aware of BIA-ALCL. Due to the risk of false negative results of fine needle aspiration, clinical suspicion of BIA-ALCL should drive clinicians' choices, aside from cytological results. In the present case, surgical capsulectomy of the abnormal periprosthesic tissue revealed locoregional recurrence.
Keywords: breast cancer; breast implant associated-anaplastic large cell lymphoma; breast seroma; case report; immediate breast reconstruction; locoregional recurrence; macro textured breast implants; residual breast tissue.
Copyright © 2021 Materazzo, Vanni, Pellicciaro, Anemona, Servadei, Giacobbi, Farinaccio, Pistolese, Perretta, Chiocchi, Bruno, Tacconi, Sadri, De Majo, Di Pasquali, Meucci, Santori, Cotesta and Buonomo.