Cutaneous Findings in SARS-CoV-2-Associated Multisystem Inflammatory Disease in Children

Allison M Blatz; Michelle Oboite; Kathleen Chiotos; Leslie Castelo-Soccio; Audrey R Odom John; Children’s Hospital of Philadelphia MIS-C Research Collaborative

doi:10.1093/ofid/ofab074

Cutaneous Findings in SARS-CoV-2-Associated Multisystem Inflammatory Disease in Children

Open Forum Infect Dis. 2021 Feb 16;8(3):ofab074. doi: 10.1093/ofid/ofab074. eCollection 2021 Mar.

Authors

Allison M Blatz¹, Michelle Oboite^{2

3}, Kathleen Chiotos^{1

4

3}, Leslie Castelo-Soccio^{2

3}, Audrey R Odom John^{1

3}; Children’s Hospital of Philadelphia MIS-C Research Collaborative

Collaborators

Children’s Hospital of Philadelphia MIS-C Research Collaborative:
Hamid Bassiri, Edward M Behrens, Caroline Diorio, Julie C Fitzgerald, Therese Giglia, Michele Lambert, Whitney Petrosa, David T Teachey, Laura A Vella, Char Witmer

Affiliations

¹ Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
² Dermatology Section, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
³ Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
⁴ Division of Critical Care Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Abstract

Rash is a common feature of multisystem inflammatory syndrome in children (MIS-C), a postinfectious hyperinflammatory disease associated with prior severe acute respiratory syndrome coronavirus 2 infection. Because the differential diagnosis of fever and rash in children is broad, understanding clinical characteristics of MIS-C may assist with diagnosis. Here we describe the cutaneous findings observed in a series of children with MIS-C-associated rash.

Keywords: MIS-C; SARS-CoV-2; pediatric infectious diseases; rash.

Abstract

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