The human liver-type pyruvate kinase (PKL) gene is on chromosome 1 at band q21

Cytogenet Cell Genet. 1988;47(3):132-3. doi: 10.1159/000132530.

Abstract

Pyruvate kinase (PK) is an important enzyme for ATP production in the glycolytic pathway. Deficiency of this enzyme in erythrocytes is characterized by hemolytic anemia. Using in situ hybridization, we have mapped the human liver-type pyruvate kinase gene (PKL) to band q21 of chromosome 1.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Banding
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 1*
  • Humans
  • Karyotyping
  • Liver / enzymology*
  • Pyruvate Kinase / deficiency
  • Pyruvate Kinase / genetics*

Substances

  • Pyruvate Kinase