Primary SADI-S in Chinese with Diabetes and BMI < 35 kg/m2: a Retrospective Study with 2-Year Follow-up

Obes Surg. 2021 Jul;31(7):3116-3122. doi: 10.1007/s11695-021-05371-4. Epub 2021 Mar 31.

Abstract

Background: Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is a bariatric procedure based on the standard duodenal switch surgery. It was first introduced in 2007 as a procedure for individuals with clinically severe obesity. Till date, primary SADI-S has not been used on Chinese with diabetes and body mass index (BMI) < 35 kg/m2.

Objectives: Here, we account the use of this novel surgery in Chinese with diabetes and BMI < 35 kg/m2.

Methods: All relevant medical information, involving patients with diabetes and BMI < 35 kg/m2, who received primary SADI-S at Beijing Shijitan Hospital from June 2017 to December 2018, was retrospectively assessed.

Results: Twenty-six patients were selected for evaluation, and all of them completed a 2-year follow-up. The age, diabetic duration, and preoperative BMI were 35.5 (range 20-63) years, 3.5 (range 0.5-18) years, and 34.40 (range 28.74-34.96) kg/m2, respectively. At 24 months, the percentage of total body weight loss (%TWL) and BMI were 26.26 (range 13.33-43.88) and 24.72 (range 17.96-29.07) kg/m2, respectively. There were no serious complications or sequelae within a 2-year follow-up. In addition, for diabetes, 20/23 people achieved complete remission, whereas 3 achieved partial remission.

Conclusion: SADI-S is a highly effective and feasible bariatric surgery for Chinese having diabetes and BMI < 35 kg/m2. However, care must be taken to follow a strict criteria for patient selection and to monitor patients carefully for the detection of postoperative nutritional sequelae.

Keywords: BMI< 35 kg/m2; Chinese; Obesity; Single-anastomosis duodeno–ileal bypass with sleeve gastrectomy; Type 2 diabetes mellitus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index
  • China / epidemiology
  • Diabetes Mellitus* / epidemiology
  • Duodenum / surgery
  • Follow-Up Studies
  • Gastrectomy
  • Gastric Bypass*
  • Humans
  • Middle Aged
  • Obesity, Morbid* / surgery
  • Retrospective Studies
  • Young Adult