One third of alloantibodies in patients with sickle cell disease transfused with African blood are missed by the standard red blood cell test panel

Lilian A Boateng; Henk Schonewille; Peter C Ligthart; Ahmad Javadi; Barbera Veldhuisen; Alex Osei-Akoto; Yvonne Dei-Adomakoh; Imelda Bates; C Ellen Van der Schoot

doi:10.3324/haematol.2021.278451

One third of alloantibodies in patients with sickle cell disease transfused with African blood are missed by the standard red blood cell test panel

Haematologica. 2021 Aug 1;106(8):2274-2276. doi: 10.3324/haematol.2021.278451.

Authors

Lilian A Boateng¹, Henk Schonewille², Peter C Ligthart², Ahmad Javadi², Barbera Veldhuisen², Alex Osei-Akoto³, Yvonne Dei-Adomakoh⁴, Imelda Bates⁵, C Ellen Van der Schoot²

Affiliations

¹ Centre for Capacity Research, International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Medical Diagnostics, Kwame Nkrumah University of Science and Technology, Kumasi. [email protected].
² Experimental Immunohaematology, Sanquin, Amsterdam.
³ Child Health, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Directorate of Child Health, Komfo Anokye Teaching Hospital, Kumasi.
⁴ Haematology, University of Ghana Medical School, University of Ghana, Accra, Ghana; Ghana Institute of Clinical Genetics, Korle Bu Teaching Hospital, Adult Sickle Cell Clinic, Accra.
⁵ Centre for Capacity Research, International Public Health, Liverpool School of Tropical Medicine, Liverpool.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anemia, Sickle Cell* / diagnosis
Anemia, Sickle Cell* / therapy
Erythrocyte Transfusion
Erythrocytes
Humans
Isoantibodies*

Substances

Isoantibodies

Grants and funding

Funding: this work was supported by grant GHCA-2017-18 to LB, from the Commonwealth Scholarship Commission, UK and from Sanquin Blood Supply, The Netherlands.