Glomerular lesions have rarely been reported with angioimmunoblastic lymphadenopathy (AILD). A patient with histologically documented AILD developed the nephrotic syndrome. Renal biopsy demonstrated minimal change disease. Both the lymphadenopathy and the nephrotic syndrome spontaneously remitted in this patient. Prior reports of renal disease in AILD and atypical lymphoproliferative disorders are discussed. An association between the minimal change lesions and AILD is suggested.