Topography of neurophysin-immunoreactive neurons projecting to the neurohypophysis: direct evidence as revealed by a double staining method

P H Luppi; K Kitahama; K Sakai; M Sallanon; M Jouvet

doi:10.1016/0304-3940(88)90493-4

Topography of neurophysin-immunoreactive neurons projecting to the neurohypophysis: direct evidence as revealed by a double staining method

Neurosci Lett. 1988 Apr 12;86(3):263-8. doi: 10.1016/0304-3940(88)90493-4.

Authors

P H Luppi¹, K Kitahama, K Sakai, M Sallanon, M Jouvet

Affiliation

¹ Département de Médecine Expérimentale, INSERM U52, C.N.R.S., Faculté de Medecine, Lyon, France.

PMID: 3380317
DOI: 10.1016/0304-3940(88)90493-4

Abstract

The topographic distribution of neurophysin-immunoreactive (NP-IR) cells projecting to the posterior pituitary gland has been studied in the cat using a double staining method: immunohistochemistry of neurophysin in conjunction with horseradish peroxidase (HRP) retrograde tracer technique. We found that almost all the hypothalamic NP-IR cells project directly to the neurohypophysis except those localized in the suprachiasmatic nucleus and in the caudal part of the paraventricular nucleus.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cats
Female
Horseradish Peroxidase
Hypothalamus / analysis
Hypothalamus / cytology*
Immunohistochemistry
Male
Neural Pathways / cytology
Neurophysins / analysis*
Paraventricular Hypothalamic Nucleus / analysis
Paraventricular Hypothalamic Nucleus / cytology
Pituitary Gland, Posterior / analysis
Pituitary Gland, Posterior / cytology*
Supraoptic Nucleus / analysis
Supraoptic Nucleus / cytology

Substances

Neurophysins
Horseradish Peroxidase