May-Thurner syndrome and deep vein thrombosis: A series of 8 patients

Med Clin (Barc). 2021 Jun 25;156(12):622-624. doi: 10.1016/j.medcli.2020.11.039. Epub 2021 Mar 30.
[Article in English, Spanish]

Abstract

Objectives: To analyze the prevalence of May-Thurner syndrome (MTS) among patients with deep vein thrombosis (DVT) of left lower limb (LLL), and outcomes after long-term follow-up.

Method: Retrospective observational study that included patients older than 18 diagnosed with acute DVT and MTS.

Results: Among 760 patients diagnosed with DVT in the LLL, 8 patients were diagnosed with MTS (1.05%), with a mean age of 39 years. All patients received long-term anticoagulation, with a mean of 31.9 (±25.2) months. Invasive treatment with pharmaco-mechanical thrombectomy was performed in 5 patients (62.5%). During follow-up (mean of 32.4 months), 25% of patients suffered DVT recurrence. Only 1 case presented major bleeding, and no deaths were registered.

Conclusions: May-Thurner syndrome constitutes a permanent and underdiagnosed risk factor for the development of DVT of LLL. Our findings suggest that long-term anticoagulation therapy might be considered in selected cases.

Keywords: Anticoagulación; Anticoagulation; Deep venous thrombosis; May-Thurner syndrome; Síndrome de May-Thurner; Thrombectomy; Trombectomía; Trombosis venosa profunda.

Publication types

  • Case Reports
  • Observational Study

MeSH terms

  • Adult
  • Humans
  • Lower Extremity
  • May-Thurner Syndrome* / complications
  • May-Thurner Syndrome* / diagnosis
  • May-Thurner Syndrome* / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Venous Thrombosis* / epidemiology
  • Venous Thrombosis* / etiology