Local body weight measurement of the spindle

Masahito Tanaka; Yuta Shimamoto

doi:10.1016/j.devcel.2021.03.019

Local body weight measurement of the spindle

Dev Cell. 2021 Apr 5;56(7):871-872. doi: 10.1016/j.devcel.2021.03.019.

Authors

Masahito Tanaka¹, Yuta Shimamoto²

Affiliations

¹ Physics and Cell Biology Laboratory, Department of Chromosome Science, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411-8540, Japan.
² Physics and Cell Biology Laboratory, Department of Chromosome Science, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411-8540, Japan; Department of Genetics, SOKENDAI University, Yata 1111, Mishima, Shizuoka 411-8540, Japan. Electronic address: [email protected].

PMID: 33823131
DOI: 10.1016/j.devcel.2021.03.019

Abstract

The spindle is a micron-sized chromosome segregation machine built from microtubules and many other proteins. In this issue of Developmental Cell, Biswas et al. (2021) use sophisticated imaging and Xenopus egg extracts to show that the spindle's mass density is only as much as the surrounding cytoplasm, contrary to popular belief.

Publication types

Comment

MeSH terms

Animals
Body Weight
Chromosome Segregation
Microtubules*
Spindle Apparatus*
Xenopus laevis