Modeling and presentation of vaccination coverage estimates using data from household surveys

Vaccine. 2021 Apr 28;39(18):2584-2594. doi: 10.1016/j.vaccine.2021.03.007. Epub 2021 Apr 3.

Abstract

It is becoming increasingly popular to produce high-resolution maps of vaccination coverage by fitting Bayesian geostatistical models to data from household surveys. Usually, the surveys adopt a stratified cluster sampling design. We discuss a number of crucial choices with respect to two key aspects of the map production process: the acknowledgement of the survey design in modeling, and the appropriate presentation of estimates and their uncertainties. Specifically, we consider the importance of accounting for urban/rural stratification and cluster-level non-spatial excess variation in survey outcomes, when fitting geostatistical models. We also discuss the trade-off between the geographical scale and precision of model-based estimates, and demonstrate visualization methods for mapping and ranking that emphasize the probabilistic interpretation of results. A novel approach to coverage map presentation is proposed to allow comparison and control of the overall map uncertainty. We use measles vaccination coverage in Nigeria as a motivating example and illustrate the different issues using data from the 2018 Nigeria Demographic and Health Survey.

Keywords: Bayesian model-based geostatistics; High-resolution maps; Small area estimation; Survey sampling; Uncertainty; Vaccination coverage.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Bayes Theorem
  • Humans
  • Measles* / epidemiology
  • Measles* / prevention & control
  • Nigeria
  • Vaccination
  • Vaccination Coverage*