A typical acute lymphoblastic leukemia JAK2 variant, R683G, causes an aggressive form of familial thrombocytosis when germline

Leukemia. 2021 Nov;35(11):3295-3298. doi: 10.1038/s41375-021-01239-9. Epub 2021 Apr 12.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Child
  • Female
  • Germ-Line Mutation*
  • Humans
  • Janus Kinase 2 / genetics*
  • Male
  • Pedigree
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Thrombocytosis / etiology
  • Thrombocytosis / metabolism
  • Thrombocytosis / pathology*
  • Young Adult

Substances

  • JAK2 protein, human
  • Janus Kinase 2