[Phosphorus binders: trigger for intestinal diverticula formation in an ADPKD patient]

G Ital Nefrol. 2021 Apr 14;38(2):2021-vol2.
[Article in Italian]

Abstract

Hyperphosphoremia is common in patients with chronic kidney disease and is an important risk factor in this patient population. Phosphate binding drugs are a key therapeutic strategy to reduce phosphoremia levels, although they have significant side effects especially in the gastrointestinal tract, such as gastritis, diarrhoea and constipation. We report the case of a haemodialysis-dependent patient suffering from chronic kidney disease stage V KDIGO secondary to polycystic autosomal dominant disease; treated with phosphate binders, the case was complicated by the appearance of diverticulosis, evolved into acute diverticulitis.

Keywords: acute diverticulitis; chronic kidney disease; diverticulosis; hyperphosphoremia; phosphate binding drugs; polycystic autosomal dominant disease.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Diverticulum*
  • Humans
  • Kidney Failure, Chronic*
  • Phosphorus
  • Polycystic Kidney, Autosomal Dominant* / complications
  • Renal Insufficiency, Chronic* / complications

Substances

  • Phosphorus