Yttrium-90 radioembolization in desmoplastic small round cell tumor with recurrent hepatic metastasis following hyperthermic intraperitoneal chemotherapy

Harkanwar Gill; Natalie Shahbazi; Zhongxin Yu; William Vanlandingham

doi:10.1016/j.radcr.2021.02.066

Yttrium-90 radioembolization in desmoplastic small round cell tumor with recurrent hepatic metastasis following hyperthermic intraperitoneal chemotherapy

Radiol Case Rep. 2021 Mar 27;16(6):1259-1263. doi: 10.1016/j.radcr.2021.02.066. eCollection 2021 Jun.

Authors

Harkanwar Gill¹, Natalie Shahbazi¹, Zhongxin Yu², William Vanlandingham³

Affiliations

¹ Department of Diagnostic Radiology, University of Oklahoma HSC, Oklahoma, OK 73104, USA.
² Department of Pathology, University of Oklahoma HSC, Oklahoma, OK 73104, USA.
³ Department of Interventional Radiology, University of Oklahoma HSC, Oklahoma, OK 73104, USA.

Abstract

We report a case of a 26-year-old male who was diagnosed with metastatic desmoplastic small round cell tumor initially treated with systemic chemotherapy followed by tumor debulking and hyperthermic intra-peritoneal chemotherapy. The patient was in complete remission by clinical and imaging criteria for 11 months, until he developed bi-lobar hepatic disease, which was successfully treated with selective internal radiation therapy by Yttrium-90. The patient demonstrated liver-specific complete response on follow-up imaging obtained 18 months after the procedure.

Keywords: Desmoplastic tumor; Hepatic metastasis; Radioembolization; Yttrium 90.

Publication types

Case Reports