In 2019, the Public Health Agency of Barcelona, Spain, was notified of a vaccine-derived poliovirus infection. The patient had an underlying common variable immunodeficiency and no signs of acute flaccid paralysis. We describe the ongoing coordinated response to contain the infection, which included compassionate-use treatment with pocapavir.
Keywords: Barcelona; Spain; adverse effects; complications; disease eradication; immunologic deficiency syndromes; oral; poliovirus vaccine; surveillance; vaccine-preventable diseases; vaccines; viruses.