We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin-producing Escherichia coli. We genotypically identified the isolate as OX18:H2. Whole-genome sequencing revealed 3 potentially pathogenic lineages (OX18:H2, H19, and H34) that have been continuously isolated in Japan.
Keywords: Bacteria; E. coli; Japan; OX18; Og-typing; STEC; Shiga toxin–producing Escherichia coli; enteric infections; food safety; foodborne pathogens; whole-genome sequencing.