Two new derivatives of 8-prenyl-5,7-dihydroxycoumarin from the stems of Streblus ilicifolius (S.Vidal) Corn

Nat Prod Res. 2022 Oct;36(19):4967-4972. doi: 10.1080/14786419.2021.1914611. Epub 2021 May 3.

Abstract

From the EtOAc-soluble extract of the stems of Streblus ilicifolius (Moraceae), two new secondary metabolites named strebluses A (1) and B (2) were isolated. Their chemical structures have been concluded based on the chemical derivatisation and the spectroscopic interpretation. All compounds have been tested for their tyrosinase inhibitory activity. They showed weaker inhibitory activity than that of kojic acid (IC50, 44.6 µM).[Formula: see text].

Keywords: Moraceae; Streblus ilicifolius; strebluses; tyrosinase.

MeSH terms

  • Monophenol Monooxygenase
  • Moraceae* / chemistry
  • Neoprene
  • Plant Extracts / pharmacology
  • Zea mays*

Substances

  • Plant Extracts
  • prenyl
  • Neoprene
  • Monophenol Monooxygenase