Revision of the ARRIVE guidelines: rationale and scope

Nathalie Percie du Sert; Viki Hurst; Amrita Ahluwalia; Sabina Alam; Douglas G Altman; Marc T Avey; Monya Baker; William Browne; Alejandra Clark; Innes C Cuthill; Ulrich Dirnagl; Michael Emerson; Paul Garner; David W Howells; Natasha A Karp; Catriona J MacCallum; Malcolm Macleod; Ole Petersen; Frances Rawle; Penny Reynolds; Kieron Rooney; Emily S Sena; Shai D Silberberg; Thomas Steckler; Hanno Würbel; Stephen T Holgate

doi:10.1136/bmjos-2018-000002

Revision of the ARRIVE guidelines: rationale and scope

BMJ Open Sci. 2018 Jun 12;2(1):e000002. doi: 10.1136/bmjos-2018-000002.

Authors

Nathalie Percie du Sert¹, Viki Hurst¹, Amrita Ahluwalia², Sabina Alam³, Douglas G Altman⁴, Marc T Avey⁵, Monya Baker⁶, William Browne⁷, Alejandra Clark⁸, Innes C Cuthill⁷, Ulrich Dirnagl⁹, Michael Emerson¹⁰, Paul Garner¹¹, David W Howells¹², Natasha A Karp¹³, Catriona J MacCallum¹⁴, Malcolm Macleod¹⁵, Ole Petersen¹⁶, Frances Rawle¹⁷, Penny Reynolds¹⁸, Kieron Rooney¹⁹, Emily S Sena¹⁵, Shai D Silberberg²⁰, Thomas Steckler²¹, Hanno Würbel²², Stephen T Holgate²³

Affiliations

¹ NC3Rs, London, UK.
² Queen Mary University of London, London, UK.
³ F1000 Research, London, UK.
⁴ University of Oxford, Oxford, UK.
⁵ ICF Canada, Ottawa, Ontario, Canada.
⁶ Nature, San Francisco, California, USA.
⁷ University of Bristol, Bristol, UK.
⁸ PLOS ONE, London, UK.
⁹ QUEST-Center for Transforming Biomedical Research, Berlin Institute of Health (BIH), Berlin, Germany.
¹⁰ Imperial College London, London, UK.
¹¹ Liverpool School of Tropical Medicine, Liverpool, UK.
¹² University of Tasmania, Hobart, Tasmania, Australia.
¹³ Quantitative Biology, Discovery Science, IMED Biotech Unit, Cambridge, UK.
¹⁴ Hindawi, London, UK.
¹⁵ Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
¹⁶ Cardiff University, Cardiff, UK.
¹⁷ Medical Research Council, London, UK.
¹⁸ University of Florida, Gainesville, Florida, USA.
¹⁹ University of Sydney, Sydney, New South Wales, Australia.
²⁰ National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.
²¹ Janssen Pharmaceutica NV, Beerse, Belgium.
²² University of Bern, Bern, Switzerland.
²³ University of Southampton, Southampton, UK.

Abstract

In 2010, the NC3Rs published the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines to improve the reporting of animal research. Despite considerable levels of support from the scientific community, the impact on the quality of reporting in animal research publications has been limited. This position paper highlights the strategy of an expert working group established to revise the guidelines and facilitate their uptake. The group's initial work will focus on three main areas: prioritisation of the ARRIVE items into a tiered system, development of an explanation and elaboration document, and revision of specific items.

Abstract

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