Lipid metabolism and classification of hyperlipaemias

Clin Investig Arterioscler. 2021 May:33 Suppl 1:3-9. doi: 10.1016/j.arteri.2020.12.008.
[Article in English, Spanish]

Abstract

This chapter summarises, and updates, lipid metabolism. Both pathways, exogenous metabolisms route via the chylomicrons, and the endogenous pathway of very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL). The reverse cholesterol metabolism will also be mentioned. It also includes the current classification of hyperlipidaemias or hyperlipoproteinaemias, with a reminder of the phenotype classification, and further developments of the aetiological classification. Both parts have updated references, with which knowledge of this vast subject can be expanded.

Keywords: Chylomicrons; Clasificación de las hiperlipidemias; Classification of hyperlipidaemias; Lipid metabolism; Metabolismo lipídico; Metabolismo reverso; Quilomicrones; Reverse metabolism; VLDL-LDL.

MeSH terms

  • Cholesterol / metabolism*
  • Chylomicrons / metabolism
  • Humans
  • Hyperlipidemias / blood
  • Hyperlipidemias / classification*
  • Lipid Metabolism / physiology*
  • Lipoproteins, LDL / metabolism
  • Lipoproteins, VLDL / metabolism

Substances

  • Chylomicrons
  • Lipoproteins, LDL
  • Lipoproteins, VLDL
  • Cholesterol