CD28 Superagonist Shock and Blockage of Motogenic T Cell Cascade

Front Immunol. 2021 Apr 21:12:670864. doi: 10.3389/fimmu.2021.670864. eCollection 2021.

Author

Karl-Gösta Sundqvist¹

Affiliation

¹ Department of Laboratory Medicine, Division of Clinical Immunology, Karolinska Institute and Clinical Immunology and Transfusion Medicine Karolinska University Hospital, Stockholm, Sweden.

No abstract available

Keywords: CD28; activation; adhesion; costimulation; motiity.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antibodies, Monoclonal, Humanized / pharmacology*
CD28 Antigens / agonists*
Cell Movement
Cytokine Release Syndrome / immunology*
Humans
Low Density Lipoprotein Receptor-Related Protein-1 / metabolism
Lymphocyte Activation
Mice
Peptide Hydrolases / metabolism
Receptors, Antigen, T-Cell / metabolism*
Signal Transduction
T-Lymphocytes / immunology*
Thrombospondin 1 / metabolism

Substances

Antibodies, Monoclonal, Humanized
CD28 Antigens
LRP1 protein, human
Low Density Lipoprotein Receptor-Related Protein-1
Receptors, Antigen, T-Cell
Thrombospondin 1
Peptide Hydrolases
TGN-1412