Endemic SARS-CoV-2 Polymorphisms Can Cause a Higher Diagnostic Target Failure Rate than Estimated by Aggregate Global Sequencing Data
J Clin Microbiol
.
2021 Jul 19;59(8):e0091321.
doi: 10.1128/JCM.00913-21.
Epub 2021 Jul 19.
Authors
Daniel D Rhoads
1
,
David Plunkett
1
,
Joy Nakitandwe
1
,
Andrew Dempsey
1
,
Zheng Jin Tu
1
,
Gary W Procop
1
,
David Bosler
1
,
Brian P Rubin
1
,
Michael J Loeffelholz
2
,
Jay E Brock
1
Affiliations
1
Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
2
Cepheid, Sunnyvale, California, USA.
PMID:
33972454
PMCID:
PMC8288267
DOI:
10.1128/JCM.00913-21
No abstract available
Keywords:
PCR; SARS-CoV-2; mutation; nucleocapsid gene; variant.
Publication types
Letter
MeSH terms
COVID-19*
Genome, Viral
Humans
RNA, Viral
SARS-CoV-2*
Substances
RNA, Viral