A layer-by-layer assembled D/L-arginine-calix[4]arene-Si-surface for macroscopic enantio-selective discrimination of (R)/(S)-ibuprofen

Xiong Li; Yingying Yang; Jiaxin Quan; Jin Zhang; Ming Cheng; Hewei Yan; Siyun Zhang; Lei Yang; Zhiyan Lu; Haibing Li

doi:10.1039/d1cc01307f

A layer-by-layer assembled D/L-arginine-calix[4]arene-Si-surface for macroscopic enantio-selective discrimination of (R)/(S)-ibuprofen

Chem Commun (Camb). 2021 Jun 8;57(46):5706-5709. doi: 10.1039/d1cc01307f.

Authors

Xiong Li¹, Yingying Yang², Jiaxin Quan², Jin Zhang², Ming Cheng², Hewei Yan², Siyun Zhang², Lei Yang², Zhiyan Lu³, Haibing Li²

Affiliations

¹ Department of ultrasound, Zhongnan Hospital, Wuhan University, Wuhan 430071, China. [email protected].
² Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. [email protected].
³ Department of Forensic Medicine, Zhongnan Hospital of Wuhan University, No. 169 East Lake Road, Wuchang District, Wuhan 430071, Hubei, China. [email protected].

PMID: 33982718
DOI: 10.1039/d1cc01307f

Abstract

Chiral arginine was introduced by layer-by-layer assembly onto a calix[4]arene-diacid modified silica surface to control the adsorption of different kinds of ibuprofen droplets. The droplet of (S)-ibuprofen slid off rapidly, whereas the droplet of (R)-ibuprofen absorbed on the modified surface.

MeSH terms

Arginine / chemistry*
Calixarenes / chemistry*
Ibuprofen / analysis*
Molecular Structure
Particle Size
Phenols / chemistry*
Silicon Dioxide / chemistry*
Stereoisomerism
Surface Properties

Substances

Phenols
calix(4)arene
Calixarenes
Silicon Dioxide
Arginine
Ibuprofen