The effects of breaking sedentary time with different intensity exercise bouts on energy metabolism: A randomized cross-over controlled trial

Nutr Metab Cardiovasc Dis. 2021 Jun 7;31(6):1879-1889. doi: 10.1016/j.numecd.2021.03.006. Epub 2021 Apr 6.

Abstract

Background and aims: Breaking up sedentary periods, particularly with light activity, increases total energy expenditure (EE), and helps provide better glycemic control. However, the effects of activities of various intensities to interrupt prolonged sedentary time are unclear. The purpose of the present study was to examine potential differences in glycemic control and EE from breaking up sedentary time with short exercise bouts of different intensities.

Methods and results: Nine overweight/obesity young men underwent whole body indirect calorimetry at 19:00 on day 1 and stayed overnight. After awakening on day 2, they performed short duration jogging every 30 min over 8 h (16-time bouts in total) under 3 different conditions with the same running distance: (1) lactate threshold (LT) for 2 min, (2) 60% LT for 200 s, and (3) onset of blood lactate accumulation (OBLA) for 75 s. The 24-h EE and interstitial glucose concentration (from 8:00 to 19:00 on day 2) was continuously measured throughout the trials. The standard deviation during intervention and indexes of postprandial of the interstitial glucose concentration was significantly lower at LT and OBLA than at 60% LT (p < 0.05). The 24-h EE was not significantly different among conditions, but EE at OBLA during intervention was slightly but significantly higher than at 60% LT and LT.

Conclusion: Breaking up sedentary time with short-duration jogging at LT and with OBLA intensities may have better glycemic control and increased use of carbohydrate as a fuel, while short-duration a jogging at OBLA intensity may increase EE.

Trial registration: UMIN000041361.

Keywords: Breaking sedentary time; Continuous glucose monitoring; Energy expenditure; Exercise intensity; Postprandial glucose.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / blood
  • Blood Glucose / metabolism
  • Calorimetry, Indirect
  • Cross-Over Studies
  • Energy Intake
  • Energy Metabolism*
  • Humans
  • Japan
  • Lactic Acid / blood
  • Male
  • Meals
  • Obesity / blood
  • Obesity / diagnosis
  • Obesity / physiopathology
  • Obesity / therapy*
  • Physical Conditioning, Human*
  • Running*
  • Sedentary Behavior*
  • Time Factors
  • Young Adult

Substances

  • Biomarkers
  • Blood Glucose
  • Lactic Acid

Associated data

  • JPRN/UMIN000041361