First report of human infection caused by Colletotrichum chlorophyti occurring in a post-corneal transplant patient with endophthalmitis

Alberto E Paniz-Mondolfi; Steven Agemy; Connie Cañete-Gibas; Melissa R Gitman; Codrin E Iacob; Inna Necula; Ching-Yi Wang; Lourdes A Delgado Noguera; Carmita Sanders; Nathan P Wiederhold; Emilia M Sordillo; Michael D Nowak

doi:10.1016/j.mmcr.2021.04.002

First report of human infection caused by Colletotrichum chlorophyti occurring in a post-corneal transplant patient with endophthalmitis

Med Mycol Case Rep. 2021 Apr 21:32:73-76. doi: 10.1016/j.mmcr.2021.04.002. eCollection 2021 Jun.

Affiliations

¹ Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, NY, USA.
² New York Retina Consultants, NY, USA.
³ New York Eye and Ear Infirmary of Mount Sinai, NY, USA.
⁴ Instituto de Investigaciones Biomedicas IDB/ Incubadora Venezolana de la Ciencia, Emerging Pathogens Network, Cabudare, Venezuela.
⁵ Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, TX, USA.

Abstract

Keratomycosis or mycotic keratitis is recognized as one of the major causes of ophthalmic morbidity worldwide. The most common organisms linked to keratomycosis include Candida spp., Fusarium spp., and Aspergillus spp. However, varieties of saprobic fungi have been reported as causative agents of keratomycosis. Amongst these are members of the genus Colletotrichum. Herein we present the first reported case of C. chlorophyti infection in a post-corneal transplant patient, suggesting an increasing role for Colletotrichum species as emerging human pathogens, particularly in the transplant population.

Keywords: Colletotrichum chlorophyti; Emerging; Fungal; Keratitis; Pathogen.

Publication types

Case Reports