Genomic description and characterization of Nigeribacterium massiliense gen. nov., sp. nov., isolated from the human gut

Microbes Infect. 2021 Sep-Oct;23(8):104842. doi: 10.1016/j.micinf.2021.104842. Epub 2021 May 19.

Abstract

Strain Marseille-P1302 was isolated from the stool of a 2-year-old Nigerian boy suffering from Kwashiorkor, a form of severe acute malnutrition. The strain grows in aerobic atmosphere and bacterial cells are Gram-positive cocci ranging in diameter from 0.8 to 1 μm. Among species with standing in nomenclature, strain Marseille-P1302 exhibited a highest 16S rRNA sequence similarity of 94.97% with Brevilactibacter flavus strain VG341T, but was phylogenetically-closest to Brevilactibacter sinopodophylli strains KCTC 33808T. The draft genome of strain Marseille-P1302 was 2,934,258-bp-long with a 70.38% G + C content, and contained 2704 protein-coding genes and 55 RNAs that included 9 rRNA genes. On the basis of these data, we propose the creation of the new genus Nigeribacterium gen. nov., with strain Marseille-P1302T (= CSUR P1302 = DSM 29084) being the type strain of the new species Nigeribacterium. massiliense gen. nov., sp. nov.

Keywords: Culturomics; Genomics; Nigeribacterium massiliense; Taxono-genomics; Taxonomy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Composition
  • Child, Preschool
  • DNA, Bacterial / genetics
  • Genomics*
  • Humans
  • Male
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics

Substances

  • DNA, Bacterial
  • RNA, Ribosomal, 16S