Single VHH-directed BCMA CAR-T cells cause remission of relapsed/refractory multiple myeloma

Leukemia. 2021 Oct;35(10):3002-3006. doi: 10.1038/s41375-021-01269-3. Epub 2021 May 24.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • B-Cell Maturation Antigen / immunology*
  • Drug Resistance, Neoplasm*
  • Humans
  • Immunoglobulin Heavy Chains / genetics
  • Immunoglobulin Heavy Chains / metabolism*
  • Immunotherapy, Adoptive / methods*
  • Multiple Myeloma / immunology
  • Multiple Myeloma / pathology
  • Multiple Myeloma / therapy*
  • Neoplasm Recurrence, Local / immunology
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / therapy*
  • Remission Induction
  • Single-Chain Antibodies / genetics
  • Single-Chain Antibodies / metabolism*

Substances

  • B-Cell Maturation Antigen
  • Immunoglobulin Heavy Chains
  • Single-Chain Antibodies