Missing Internal Limiting Membrane during Macular Hole Repair in Alport Syndrome

Sarah G Chaudhry; Gerald Liew; Adrian T Fung

doi:10.1159/000513420

Missing Internal Limiting Membrane during Macular Hole Repair in Alport Syndrome

Case Rep Ophthalmol. 2021 May 3;12(2):320-323. doi: 10.1159/000513420. eCollection 2021 May-Aug.

Authors

Sarah G Chaudhry¹, Gerald Liew^{1

2

3

4}, Adrian T Fung^{1

2

3

5}

Affiliations

¹ Westmead Hospital, Sydney, New South Wales, Australia.
² Westmead and Central Clinical Schools, Discipline of Clinical Ophthalmology and Eye Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
³ Westmead Institute of Medical Research, Westmead, New South Wales, Australia.
⁴ Faculty of Medicine and Health, The University of New South Wales, Sydney, New South Wales, Australia.
⁵ Department of Ophthalmology, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.

Abstract

The aim of this manuscript is to describe a novel retinal finding of Alport syndrome during surgical management of an associated macular hole. A retrospective chart review of a 65-year-old man with a diagnosis of Alport syndrome confirmed by renal biopsy was found to have an associated full-thickness macular hole. Pars-plana vitrectomy surgery with internal limiting membrane (ILM) peeling was attempted, but intraoperatively the ILM was found to be absent at the macula. Alport syndrome may be associated with the absence of the ILM. This can complicate attempts at macular hole repair.

Keywords: Alport syndrome; Collagen IV; Inner limiting membrane; Macular hole surgery.

Publication types

Case Reports