Exceptional Response of a Large and Symptomatic EGFR-Mutant Brain Metastasis to Osimertinib: Case Report and Review of the Literature

JCO Precis Oncol. 2021 Apr 1:5:PO.20.00485. doi: 10.1200/PO.20.00485. eCollection 2021.
No abstract available

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Acrylamides / therapeutic use*
  • Aniline Compounds / therapeutic use*
  • Antineoplastic Agents / therapeutic use*
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / genetics
  • Brain Neoplasms / pathology
  • ErbB Receptors / genetics
  • Female
  • Humans
  • Middle Aged
  • Mutation
  • Remission Induction
  • Treatment Outcome
  • Tumor Burden

Substances

  • Acrylamides
  • Aniline Compounds
  • Antineoplastic Agents
  • osimertinib
  • EGFR protein, human
  • ErbB Receptors