Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February-March 2021

Emerg Infect Dis. 2021 Aug;27(8):2169-2173. doi: 10.3201/eid2708.210887. Epub 2021 Jun 8.

Abstract

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.

Keywords: B cell; Berlin; COVID-19; Germany; SARS-CoV-2; T cell; antibody; coronavirus disease; immunity; mRNA; outbreak; phylogeny; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccine; viruses; zoonoses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Berlin
  • COVID-19*
  • Disease Outbreaks
  • Germany / epidemiology
  • Humans
  • Long-Term Care
  • SARS-CoV-2*
  • Vaccination