[Primary liposarcomas of the digestive tract: Diversity of clinicopathological presentations and diagnostic challenges]

Ann Pathol. 2021 Jul;41(4):399-404. doi: 10.1016/j.annpat.2021.05.004. Epub 2021 Jun 10.
[Article in French]

Abstract

Sarcomas are rare tumours that represent less than 1% of all malignant tumours in adults. Liposarcomas are among the most common malignant mesenchymal tumours. They are preferentially located in the limbs and the retroperitoneum. Liposarcomas primarily arising in the digestive tract are exceptional with a few cases reported in the literature. Their clinical presentation is variable and the symptoms are not specific. Anatomopathological examination remains the gold standard for the diagnosis and the classification of these tumours, which are divided into 5 histological types according to the 5th edition of the WHO classification of soft tissue tumours. We report two observations of unusual digestive liposarcomas, located in the oesophagus and the colon, emphasizing the variability of the diagnostic challenges, depending on the clinical presentation, the histological type and the analysed material.

Keywords: Colon; Côlon; Digestive tract; Giant fibrovascular polyp; Gène MDM2; Liposarcoma; Liposarcome; MDM2 gene; Oesophagus; Polype géant fibrovasculaire; Tube digestif; Œsophage.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Gastrointestinal Tract
  • Humans
  • Liposarcoma* / diagnosis
  • Sarcoma*
  • Soft Tissue Neoplasms*