Comparison of the improvement of flow-mediated dilatation in patients with acute coronary syndrome versus stable angina after six-month cardiac rehabilitation

Cardiovasc J Afr. 2021;32(3):123-128. doi: 10.5830/CVJA-2020-022. Epub 2021 Jun 8.

Abstract

Background: We investigated whether the improvement in endothelial function, measured using flow-mediated dilatation (FMD), an important predictor of cardiovascular outcomes, was comparable in acute coronary syndrome (ACS) versus stable angina patients after percutaneous coronary intervention (PCI) and a six-month cardiac rehabilitation (CR) programme.

Methods: We analysed the results from 119 patients who completed a six-month CR programme after successful PCI for stable angina (n = 50) and ACS (n = 69).

Results: After six months of CR, the results of FMD were significantly improved in both groups. There were no significant between-group differences in the FMD results at the six-month follow up.

Conclusions: After successful PCI and a six-month CR programme, FMD values were equally improved in both stable angina and ACS patients.

Keywords: coronary disease; endothelial function; exercise training.

MeSH terms

  • Acute Coronary Syndrome / diagnostic imaging
  • Acute Coronary Syndrome / rehabilitation*
  • Adult
  • Angina, Stable / diagnostic imaging
  • Angina, Stable / rehabilitation*
  • Cardiac Rehabilitation
  • Dilatation
  • Exercise Therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Percutaneous Coronary Intervention / adverse effects
  • Quality of Life