Neuronal figure-ground responses in primate primary auditory cortex

Cell Rep. 2021 Jun 15;35(11):109242. doi: 10.1016/j.celrep.2021.109242.

Abstract

Figure-ground segregation, the brain's ability to group related features into stable perceptual entities, is crucial for auditory perception in noisy environments. The neuronal mechanisms for this process are poorly understood in the auditory system. Here, we report figure-ground modulation of multi-unit activity (MUA) in the primary and non-primary auditory cortex of rhesus macaques. Across both regions, MUA increases upon presentation of auditory figures, which consist of coherent chord sequences. We show increased activity even in the absence of any perceptual decision, suggesting that neural mechanisms for perceptual grouping are, to some extent, independent of behavioral demands. Furthermore, we demonstrate differences in figure encoding between more anterior and more posterior regions; perceptual saliency is represented in anterior cortical fields only. Our results suggest an encoding of auditory figures from the earliest cortical stages by a rate code.

Keywords: A1; auditory cortex; auditory figure; auditory figure-ground segregation; auditory object; non-human primate; perceptual organization; rhesus macaque; scene analysis; stochastic figure-ground stimulus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Auditory Cortex / physiology*
  • Auditory Perception / physiology
  • Female
  • Macaca mulatta
  • Male
  • Motor Activity / physiology
  • Neurons / physiology*
  • Stochastic Processes