Inflammatory myophibroblastic tumor of the proximal ileon in a patient with complicated umbilical hernia: A case report and literature review

Int J Surg Case Rep. 2021 Jul:84:106091. doi: 10.1016/j.ijscr.2021.106091. Epub 2021 Jun 8.

Abstract

Introduction: Inflammatory myofibroblastic tumors are neoplasms that occur infrequently, mainly affects children and young adults. It is an intermediate grade fibrotic multinodular neoplasm.

Description of the case: We present the case of a 47-year-old female patient, who underwent emergency umbilical hernioplasty, later developed intestinal obstruction secondary to an inflammatory myofibroblastic tumor.

Discussion: In 1939 Brunn described it for the first time, later in 1954 Umiker named it "Inflammatory Myofibroblastic Tumor". The symptoms are nonspecific. In 15 to 40% of patients they are asymptomatic. Cells positive for actin, smooth muscle, vimentin and desmin, in 3367% of cases the cells are positive for ALK, which is present in some malignant lesions. The recommended treatment is radical resection.

Conclusion: The diagnosis is established by histopathological study, surgery is the cornerstone of treatment.

Keywords: Inflammatory myofibroblastic tumor; Intestinal obstruction; Low-grade sarcoma.