Abstract
Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Antibodies, Viral / blood
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Antibodies, Viral / immunology*
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Bayes Theorem
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COVID-19 / diagnosis*
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COVID-19 / epidemiology
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COVID-19 / virology
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Enzyme-Linked Immunosorbent Assay
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Epidemics
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Female
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Humans
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Immunoglobulin G / blood
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Immunoglobulin G / immunology
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Kenya / epidemiology
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Male
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Middle Aged
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Prevalence
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SARS-CoV-2 / immunology*
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SARS-CoV-2 / metabolism
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SARS-CoV-2 / physiology
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Seroepidemiologic Studies
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Spike Glycoprotein, Coronavirus / immunology*
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Spike Glycoprotein, Coronavirus / metabolism
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Young Adult
Substances
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Antibodies, Viral
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Immunoglobulin G
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Spike Glycoprotein, Coronavirus
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spike protein, SARS-CoV-2