Fibromuscular dysplasia in a middle-aged transgender man: The role of hormones in disease pathogenesis

Heather L Wheat; Ben P Alencherry; Teresa L Carman; Mehdi H Shishehbor; Heather L Gornik

doi:10.1177/2050313X211025922

Fibromuscular dysplasia in a middle-aged transgender man: The role of hormones in disease pathogenesis

SAGE Open Med Case Rep. 2021 Jun 14:9:2050313X211025922. doi: 10.1177/2050313X211025922. eCollection 2021.

Authors

Heather L Wheat¹, Ben P Alencherry², Teresa L Carman³, Mehdi H Shishehbor³, Heather L Gornik³

Affiliations

¹ Department of Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
² Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
³ Department of Cardiovascular Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Abstract

Fibromuscular dysplasia is an uncommon non-inflammatory arteriopathy. Hormonal factors are believed to play a role in disease pathogenesis given the overwhelming female predominance of this disease. We describe a case of a 56-year-old transgender man on prolonged testosterone therapy diagnosed with renal fibromuscular dysplasia after presenting with hypertensive urgency.

Keywords: Fibromuscular dysplasia; angiography; hypertension.

Publication types

Case Reports