The First Case of Multisystem Inflammatory Syndrome in Adult after COVID-19 in Korea

J Korean Med Sci. 2021 Jun 28;36(25):e181. doi: 10.3346/jkms.2021.36.e181.

Abstract

Multisystem inflammatory disease in children is a Kawasaki disease like illness occurring after severe acute respiratory syndrome coronavirus 2 infection in children. As the pandemic progresses, similar syndromes were also reported in adult with a decreased incidence. Multisystem inflammatory syndrome in adults (MIS-A) can be characterized with shock, heart failure, and gastrointestinal symptoms with elevated inflammatory markers after coronavirus disease 2019 (COVID-19) infection. Herein, we describe the first case of MIS-A in South Korea. A 38-year-old man presented to our hospital with a 5-day history of abdominal pain and fever. He had been treated with antibiotics for 5 days at the previous hospital, but symptoms had worsened and he had developed orthopnea on the day of presentation. He suffered COVID-19 six weeks ago. Laboratory data revealed elevated white blood cell counts with neutrophil dominance, C-reactive protein, and B-type natriuretic peptide. Chest X-ray showed normal lung parenchyme and echocardiography showed severe biventricular failure with normal chamber size. We diagnosed him as MIS-A and treated with intravenous immunoglobulin and steroid.

Keywords: Adult; COVID-19; Multisystem Inflammatory Syndrome.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / etiology
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • COVID-19 / complications*
  • Fever / etiology
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Male
  • Republic of Korea
  • SARS-CoV-2*
  • Shock / etiology
  • Shock / therapy
  • Systemic Inflammatory Response Syndrome / drug therapy
  • Systemic Inflammatory Response Syndrome / etiology*

Substances

  • Adrenal Cortex Hormones
  • Immunoglobulins, Intravenous