Successful use of crushed formulation of dabrafenib and trametinib in a pediatric glioneural tumor

Pediatr Blood Cancer. 2021 Oct;68(10):e29187. doi: 10.1002/pbc.29187. Epub 2021 Jun 29.

Authors

Tania Mamdouhi¹, Anshul Vagrecha², Alan A Johnson^{1

3}, Carolyn Fein Levy^{1

2}, Mark Atlas^{1

2}, Julie I Krystal^{1

2}

Affiliations

¹ Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
² Division of Hematology/Oncology and Cellular Therapy, Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New York, USA.
³ Division of Neuroradiology, Department of Radiology, Long Island Jewish Medical Center, New Hyde Park, New York, USA.

PMID: 34185373
DOI: 10.1002/pbc.29187

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Antineoplastic Combined Chemotherapy Protocols
Child
Humans
Imidazoles / therapeutic use*
Mutation
Nervous System Neoplasms / drug therapy*
Oximes / therapeutic use*
Pyridones / therapeutic use*
Pyrimidinones / therapeutic use*

Substances

Imidazoles
Oximes
Pyridones
Pyrimidinones
trametinib
dabrafenib