A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19

Eur Respir J. 2021 Oct 14;58(4):2100673. doi: 10.1183/13993003.00673-2021. Print 2021 Oct.

Abstract

The inhaled lung-selective pan-JAK inhibitor nezulcitinib appears generally well tolerated in hospitalised patients with severe #COVID-19, with trends for improved oxygenation and clinical status, shortened hospitalisation, and fewer deaths versus placebo https://bit.ly/35Xs1Rf

Publication types

  • Clinical Trial, Phase II
  • Letter

MeSH terms

  • Administration, Inhalation
  • COVID-19*
  • Humans
  • Janus Kinase Inhibitors*
  • Janus Kinases
  • SARS-CoV-2

Substances

  • Janus Kinase Inhibitors
  • Janus Kinases