Burkitt Lymphoma Presenting as Perforated Appendicitis

Am Surg. 2022 Mar;88(3):547-548. doi: 10.1177/00031348211029854. Epub 2021 Jul 4.

Abstract

Appendicitis is the most common indication for an emergent abdominal operation in the pediatric population. Fewer than .015% of patients who undergo appendectomy for presumed appendicitis are diagnosed with primary lymphoma after evaluation of pathology specimen. 1 Of these primary lymphomas, 29.5% are Burkitt lymphoma. Burkitt lymphoma is an aggressive B-cell lymphoma characterized by translocation and dysregulation of the c-Myc gene. Intraabdominal extranodal Burkitt lymphoma has a polymorphic presentation that includes bowel obstruction, intussusception, and appendicitis. Here we report a case of an adolescent patient who was initially admitted for medical management of perforated appendicitis but was diagnosed with Burkitt lymphoma during his hospital course.

Keywords: Burkitt lymphoma; complicated appendicitis; pediatric.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / chemically induced
  • Adolescent
  • Anti-Bacterial Agents / adverse effects
  • Appendectomy
  • Appendicitis / diagnostic imaging
  • Appendicitis / etiology*
  • Appendicitis / surgery
  • Burkitt Lymphoma / complications*
  • Burkitt Lymphoma / diagnosis
  • Humans
  • Male

Substances

  • Anti-Bacterial Agents