Malnutrition and Alcohol-Associated Hepatitis

Clin Liver Dis. 2021 Aug;25(3):557-570. doi: 10.1016/j.cld.2021.03.002. Epub 2021 May 26.

Abstract

Malnutrition is common in alcohol-associated hepatitis (AH); almost all patients with severe AH have some component of malnutrition. The classic phenotype of malnutrition in AH is sarcopenia, but this has become more difficult to discern clinically as patients have become more obese. Patients with AH are often drinking 10 to 15 standard drinks per day. This substantial alcohol consumption becomes a major source of calories, but these are considered "empty" calories that contain little nutritional value. Malnutrition is associated with liver complications, such as hepatic encephalopathy, and worse liver outcomes. Nutrition support can improve nutrition status and reduce complications.

Keywords: Alcohol-associated hepatitis (AH); Malnutrition; Micronutrients; Nutrition; Standard drink.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Hepatic Encephalopathy*
  • Hepatitis, Alcoholic*
  • Humans
  • Malnutrition* / epidemiology
  • Malnutrition* / etiology
  • Nutritional Status
  • Nutritional Support