Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil

Rev Soc Bras Med Trop. 2021 Jul 2:54:e00762021. doi: 10.1590/0037-8682-0076-2021. eCollection 2021.

Abstract

Introduction: Leptospirosis and brucellosis cause immunosuppression that worsens the clinical condition of people living with HIV/AIDS (PLWHA). We investigated the serological profile and risk factors of PLWHA.

Methods: Serum samples (n=238) were researched for Brucella spp. antibodies using Rose Bengal and tube agglutination tests and Leptospira spp. antibodies using the microscopic agglutination test.

Results: All samples were negative for Brucella spp. For leptospirosis, four samples (1.69%) were positive, and Andamana was the prevalent serovar.

Conclusions: Low or no detection of these zoonoses does not reduce their importance in PLWHA. Vigilant, educational, and preventive measures should be adopted.

MeSH terms

  • Agglutination Tests
  • Animals
  • Antibodies, Bacterial
  • Brazil / epidemiology
  • Brucellosis* / complications
  • Brucellosis* / epidemiology
  • HIV
  • HIV Infections* / complications
  • HIV Infections* / epidemiology
  • Hospitals
  • Humans
  • Leptospira*
  • Leptospirosis* / complications
  • Leptospirosis* / epidemiology
  • Referral and Consultation
  • Risk Factors

Substances

  • Antibodies, Bacterial