Imaging considerations for thermal and radiotherapy ablation of primary and metastatic renal cell carcinoma

Abdom Radiol (NY). 2021 Nov;46(11):5386-5407. doi: 10.1007/s00261-021-03178-6. Epub 2021 Jul 10.

Abstract

Ablative (percutaneous and stereotactic) thermal and radiotherapy procedures for management of both primary and metastatic renal cell carcinoma are increasing in popularity in clinical practice. Data suggest comparable efficacy with lower cost and morbidity compared to nephrectomy. Ablative therapies may be used alone or in conjunction with surgery or chemotherapy for treatment of primary tumor and metastatic disease. Imaging plays a crucial role in pre-treatment selection and planning of ablation, intra-procedural guidance, evaluation for complications, short- and long-term post-procedural surveillance of disease, and treatment response. Treatment response and disease recurrence may differ considerably after ablation, particularly for stereotactic radiotherapy, when compared to conventional surgical and chemotherapies. This article reviews the current and emerging role of imaging for ablative therapy of renal cell carcinoma.

Keywords: Ablation; Computed tomography; Magnetic resonance imaging; Radiotherapy; Renal cell carcinoma; Thermal.

Publication types

  • Review

MeSH terms

  • Carcinoma, Renal Cell* / diagnostic imaging
  • Carcinoma, Renal Cell* / surgery
  • Catheter Ablation*
  • Humans
  • Kidney Neoplasms* / diagnostic imaging
  • Kidney Neoplasms* / surgery
  • Neoplasm Recurrence, Local
  • Nephrectomy
  • Treatment Outcome