Pseudocirrhosis due to liver metastasis from lung adenocarcinoma

Thorac Cancer. 2021 Sep;12(17):2407-2410. doi: 10.1111/1759-7714.14084. Epub 2021 Jul 17.

Abstract

Pseudocirrhosis is a radiological diagnosis of cirrhosis without histological evidence and occurs as a complication of liver metastases from solid tumors. A 50-year-old man without any previous history of liver disease was diagnosed with adenocarcinoma of the left upper lung lobe and liver metastasis. After chemotherapy, the liver metastases shrank; however, over time, the liver shrank and showed cirrhosis-like morphological changes. His performance status deteriorated due to ascites and leg edema, and chemotherapy was terminated. Physicians treating lung adenocarcinoma with liver metastases should be aware that pseudocirrhosis is a rare but important complication that can worsen performance status (PS) and hinder treatment continuation.

Keywords: adenocarcinoma; liver metastasis; lung cancer; pseudocirrhosis.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma of Lung / drug therapy
  • Adenocarcinoma of Lung / pathology*
  • Antineoplastic Agents / therapeutic use
  • Humans
  • Liver Cirrhosis / drug therapy
  • Liver Cirrhosis / pathology*
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / secondary*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology*
  • Male
  • Middle Aged

Substances

  • Antineoplastic Agents