Age-Dependent Neutralization of SARS-CoV-2 and P.1 Variant by Vaccine Immune Serum Samples

Timothy A Bates; Hans C Leier; Zoe L Lyski; James R Goodman; Marcel E Curlin; William B Messer; Fikadu G Tafesse

doi:10.1001/jama.2021.11656

Age-Dependent Neutralization of SARS-CoV-2 and P.1 Variant by Vaccine Immune Serum Samples

JAMA. 2021 Jul 21;326(9):868-869. doi: 10.1001/jama.2021.11656. Online ahead of print.

Authors

Timothy A Bates¹, Hans C Leier¹, Zoe L Lyski¹, James R Goodman², Marcel E Curlin³, William B Messer¹, Fikadu G Tafesse¹

Affiliations

¹ Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland.
² Medical Scientist Training Program, Oregon Health & Science University, Portland.
³ Division of Infectious Diseases, Oregon Health & Science University, Portland.

Abstract

This study examines the relationship between age and neutralizing antibody titers against the SARS-CoV-2 USA-WA1/2020 strain and the P.1 variant after 2 doses of the BNT162b2 vaccine.

Grants and funding

R01 AI145835/AI/NIAID NIH HHS/United States