Lassa fever amidst the COVID-19 pandemic in Africa: A rising concern, efforts, challenges, and future recommendations

J Med Virol. 2021 Dec;93(12):6433-6436. doi: 10.1002/jmv.27219. Epub 2021 Jul 27.

Abstract

Lassa fever, caused by the Lassa virus of the Arenaviruses family, is a re-emerging public health concern that has led to 300,000 infections and 5000 deaths annually in Africa. Highly prevalent in Sierra Leone, Liberia, Guinea, Nigeria, Côte d'lvoire, Ghana, Togo, and Benin, patients infected with the virus can manifest with cough, sore throat, headache, nausea, and vomiting among other symptoms. Coexisting with the coronavirus disease 2019 (COVID-19) pandemic and its impacts, cases of Lassa fever in the African population have been reported to decrease due to hesitancy in visiting clinics that leads to unreported cases-all contributing to a silent outbreak in West Africa. Thus, to overcome current burdens, gaps, and challenges caused by Lassa fever amidst COVID-19 in Africa, various recommendations for efficient control of transmission, measures for disease containment, and strategies to correct misperceptions were made.

Keywords: Africa; COVID-19; Lassa fever; Lassa virus; endemic; infectious disease; pandemic; public health.

MeSH terms

  • Africa, Western / epidemiology
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control*
  • Disease Outbreaks / statistics & numerical data
  • Humans
  • Lassa Fever / diagnosis
  • Lassa Fever / epidemiology*
  • Lassa Fever / prevention & control*
  • Lassa virus
  • Molecular Diagnostic Techniques
  • Patient Acceptance of Health Care / statistics & numerical data*
  • Public Health
  • SARS-CoV-2
  • Viral Vaccines

Substances

  • Viral Vaccines