[Research progress on chemical constituents and pharmacological activities of iridoid glycosides in Lonicera japonica]

Zhongguo Zhong Yao Za Zhi. 2021 Jun;46(11):2746-2752. doi: 10.19540/j.cnki.cjcmm.20210108.602.
[Article in Chinese]

Abstract

As a traditional Chinese medicinal material, Lonicera japonica has a long medicinal history. The chemical constituents of Lonicera japonica are complex, mainly including iridoid glycosides, flavonoids, triterpenes, organic acids and volatile oil. Iridoid glycosides account for a higher proportion. In addition, modern pharmacological studies have shown that the iridoid glycosides have many pharmacological activities such as antivirus, anti-inflammation, anti-tumor, liver protection and lowering blood sugar. This review intends to systematically summarize the iridoid glycosides identified from Lonicera japonica and their pharmacological activities by searc-hing Chinese and English databases, in order to provide a reference for the further development and utilization of Lonicera japonica and for the improvement of quality standards of medicinal materials.

Keywords: Lonicera japonica; chemical constituent; iridoid glycosides; pharmacological activity.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents
  • Flavonoids
  • Glycosides / pharmacology
  • Iridoid Glycosides / pharmacology
  • Lonicera*
  • Plant Extracts

Substances

  • Anti-Inflammatory Agents
  • Flavonoids
  • Glycosides
  • Iridoid Glycosides
  • Plant Extracts