Transcatheter mitral valve repair using the Cardioband® system: Histopathological insights in device ingrowth and biocompatibility

J Card Surg. 2021 Oct;36(10):3869-3871. doi: 10.1111/jocs.15843. Epub 2021 Jul 26.

Abstract

Surgical implantation of a complete or incomplete ring to reduce the valve annulus and improve leaflet coaptation is the mainstay of mitral valve surgery. The Cardioband® system (Edwards Lifesciences) was designed to address the pathophysiological mechanism of annular dilatation through a catheter-based approach. We present the histopathological workup of a Cardioband® device, which had been implanted 21 months earlier in a 34-year-old male with ischemic cardiomyopathy. Device examination demonstrate a well-positioned and securely anchored device. The described tissue reactions may have an impact on choice of device and timing in case of re-do surgery.

Keywords: Cardioband; biocompatibility; mitral annuloplasty; mitral regurgitation; tissue reaction; transcatheter mitral valve repair.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Heart Valve Prosthesis Implantation*
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Mitral Valve / diagnostic imaging
  • Mitral Valve / surgery
  • Mitral Valve Annuloplasty*
  • Mitral Valve Insufficiency* / surgery
  • Treatment Outcome