Neutrophilic Dermatosis in Myelodysplastic Syndrome and Chronic Active Hepatitis C

J Investig Med High Impact Case Rep. 2021 Jan-Dec:9:23247096211037458. doi: 10.1177/23247096211037458.

Abstract

In this article, we describe a case of neutrophilic dermatosis of the dorsal hands (NDDH) complicated with myelodysplastic syndrome and chronic active hepatitis C infection. NDDH was first suggested by Galaria et al in 2000. After comparing features of NDDH with Sweet syndrome in terms of encompassing clinical, laboratory, and histological characteristics, it can be concluded that "distributional or localized variant" of Sweet syndrome is classified as NDDH. Early diagnosis and treatment can improve prognosis. Systemic glucocorticoids are the mainstay of treatment.

Keywords: coexistence of hepatitis C and Sweet syndrome; coexistence of myelodysplastic syndrome and Sweet syndrome; management of neutrophilic dermatosis of the dorsal hands; neutrophilic dermatosis of the dorsal hands.

Publication types

  • Case Reports

MeSH terms

  • Glucocorticoids / therapeutic use
  • Hand Dermatoses*
  • Hepatitis C, Chronic* / complications
  • Hepatitis C, Chronic* / drug therapy
  • Humans
  • Myelodysplastic Syndromes* / complications
  • Myelodysplastic Syndromes* / diagnosis
  • Sweet Syndrome* / diagnosis

Substances

  • Glucocorticoids